2020

 

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March 2020

Spatiotemporal regulation of type I interferon expression determines antiviral CD4+ T cell polarization.

De Giovanni M, Cutillo V, Giladi A, Maganuco CG, Medaglia C, Bono E, Di Lucia P, Giustini L, Cristofani C, Pinschewer DD, Kastenmuller W, Amit I, Kuka M, Iannacone M.

 

 
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November 2019

CXCR3 identifies human naive CD8+ T cells with enhanced effector differentiation potential.

De Simone G, Mazza EMC, Cassotta A, Davydov A, Kuka M, Zanon V, De Paoli F, Scamardella E, Metsger M, Roberto A, Pilipow K, Colombo FS, Tenedini E, Tagliafico E, Gattinoni L, Mavilio D, Peano C, Price DA, Singh SP, Farber JM, Ferrari F, Orrù V, Fiorillo E, Iannacone M*, Chudakov DM*, Sallusto F*, Lugli E 

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May 2019

Phagocytosis-shielded lentiviral vectors allow safe and robust liver gene transfer in non-human primates.

De Simone G, Mazza EMC, Cassotta A, Davydov A, Kuka M, Zanon V, De Paoli F, Scamardella E, Metsger M, Roberto A, Pilipow K, Colombo FS, Tenedini E, Tagliafico E, Gattinoni L, Mavilio D, Peano C, Price DA, Singh SP, Farber JM, Ferrari F, Orrù V, Fiorillo E, Iannacone M*, Chudakov DM*, Sallusto F*, Lugli E 

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November 2019

The role of type I interferons in CD4+ T cell differentiation.

Kuka M, De Giovanni M, Iannacone M

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October 2019

Dynamics and genomic landscape of CD8+ T cells undergoing intrahepatic priming.

Benechet AP*, De Simone G*, Di Lucia P, Cilenti F, Barbiera G, Le Bert N, Moalli F, Lusito E, Fumagalli V, Bianchessi V, Zordan P, Bono E, Giustini L, Bonilla WD, Bleriot C, Kunasegaran K, Gonzalez-Aseguinolaza G, Pinschewer DD, Kennedy PTF, Naldini L, Kuka M, Ginhoux F, Cantore A, Bertoletti A, Ostuni R, Guidotti LG, Iannacone M

2019

 

2018

 

 
 
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November 2018

The conduit system exports locally secreted IgM from lymph nodes.

DeThierry G, Kuka M, De Giovanni M, Mondor I, Brouilly I, Iannacone M*, Bajenoff M*

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July 2018

Zika virus replication in dorsal root ganglia explants causes myelin degeneration. 

Volpi VG, Pagani I, Ghezzi S, Iannacone M, D’Antonio M, Vicenzi E

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April 2018

Viral subversion of B cell responses within secondary lymphoid organs.

Kuka M, Iannacone M

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September 2018

Antioxidant metabolism in activated CD8+ T cells regulates stem-like human memory T cell formation and anti-tumor immunity.

Pilipow K, Scamardella E, Puccio S, Gautam S, De Paoli F, Mazza EMC, De Simone G, Polletti S, Buccilli M, Zanon V, Di Lucia P, Iannacone M, Gattinoni L, Lugli E 

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August 2018

Tr1 cell immunotherapy promotes transplant tolerance via de novo Tr1 cell induction in mice and is safe and effective during acute viral infection. 

Jofra T, Di Fonte R, Galvani G, Kuka M, Iannacone M, Battaglia M, Fousteri G 

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April 2018

Intravital imaging of B cell responses in lymph nodes

Sammicheli S, Kuka M, Iannacone M

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June 2018

The Rho regulator Myosin IXb enables non-lymphoid tissue seeding of protective CD8+ cells

Moalli F, Ficht X, Germann P, Vladymyrov M, Stolp B, de Vries I, Lyck RV, Balmer J, Fiocchi A, Kreutzfeld M, Merkler D, Iannacone M, Ariga A, Stoffel MH, Sharpe J, Bähler M, Sixt M, Diz-Muñoz A, Stein JV  

April 2018

Alum/TLR7 adjuvant enhances the expansion of memory B cell compartment within the draining lymph node 

Vo HTM, Baudner BC, Sammicheli S, Iannacone M, D’Oro U, Piccioli 

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February 2018

In vivo imagina of adaptive immune responses to viruses. 

De Giovanni M and Iannacone M

 

2017

 

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December 2017

Spatial reconstruction of immune niches by combining photoactivatable fluorescent reporters and single-cell RNA-seq.

DeMedaglia C*, Giladi A*, Stoler Barak L*, De Giovanni M*, Meir Salame T, Biram A, David E, Iannacone M, Shulman Z, Amit I

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November 2017

Sympathetic associated macrophages clear norepinephrine and sustain obesity.

Pirzgalska RM*, Seixas E*, Seidman JS, Link VM, Martinez Sanchez N, Mahú I, Mendes R, Gres V, Kubasova N, Morris I, Arús BA, Larabee CM, Vasques M, Tortosa F, Sousa AL, Anandan S, Tranfield E, Hahn MK, Iannacone M, Spann NJ, Glass KC, Domingos AI

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July 2017

Protein tyrosine phosphatase PTPN22 dampens T cell immune responses and drives viral persistence.

Jofra T, Di Fonte R, Kuka M, Mfarrej B, Iannacone M, Battaglia M, Fousteri G

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May 2017

In vivo chronic stimulation unveils intrinsic auto reactive potential of Wiskott-Aldrich syndrome protein-deficient B cells.

Fontana E, Radaelli E, Uva P, Cervantes-Luevano KE, Benvenuti F, Poliani PL, Iannacone M, Traggiai E, Villa A, Bosticardo M

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January 2017

Determinants of hepatic effector CD8+ T cell dynamics.

Benechet AP, Iannacone M

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November 2017

Migrating platelets are Mechano-scavengers that collect and bundle bacteria.

Gaertner F, Ahmad Z, Rosenberg G, Fan S, Nicolai L, Busch B, Yavuz G, Luckner M, Luckner M, Ishikawa-Ankerhold H, Hennel R, Benechet AP, Lorenz M, Chandraratne S, Schubert I, Helmer S, Striednig B, Stark K, Janko M, Bottcher RT, Verschoor A, Leon C, Gachet C, Gudermann T, Mederos y Schnitzler M, Pincus Z, Iannacone M, Hass R, Wanner G, Lauber K, Sixt M, Massberg S

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November 2017

Pathogen-specific B cell receptors drive chronic lymphocytic leukemia by light chain-dependent cross-reaction with autoantigens.

Jimenez de Oya N*, De Giovanni M*, Fioravanti J, Ubelhart R, Di Lucia P, Fiocchi A, Iacovelli S, Efremov DG, Caligaris-Cappio F, Jumaa H, Ghia P, Guidotti LG, Iannacone M

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July 2017

Constitutive resistance to viral infection in human CD141+ dendritic cells.

Silvin A, Yu CI, Lahaye X, Imperatore F, Brault JB, Cardinaud S, Becker C, Kwan WH, Conrad C, Maurin M, Goudot C, Marques-Ladeira S, Wang Y, Pascual V, Anguiano E, Albrecht RA, Iannacone M, Garcia-Sastre A, Goud B, Dalod M, Moris A, Merad M, Palucka CA, Manel N

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February 2017

CD8+ T cells orchestrate pDC-XCR1+ dendritic cell spatial and functional cooperatively to optimize priming.

Brewitz A, Eickhoff S, Dahling S, Quast T, Bedoui S, Kroczek RA, Kurts C, Garbi N, Barchet W, Iannacone M, Klauschen F, Kolanus W, Kaisho T, Colonna M, Germain RN, Kastenmuller W

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November 2017

Intestinal flossing keeps pathogens at bay.

Kuka M and Iannacone M

October 2017

Microcirculation in mouse live lobule: a computational fluir dynamic model based on 3D reconstruction from in vivo microscopy.

Piergiovanni M, Bianchi E, Capitani G, Li Piani I, Ganzer L, Guidotti LG, Iannacone M, Dubini G

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September 2017

Effector CD8+ T cell-derived interleukin-10 enhances liver immunopathology.

Fioravanti J, Magini D, Di Lucia P, Boni C, Benechet AP, Inverso D, Fiocchi A, Wieland S, Purcell R, Ferrari C, Chisari FV, Guidotti LG, Iannacone M

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January 2017

Intravital microscopy analysis of hepatic T cell dynamics.

Benechet AP, Ganzer K, Iannacone M

 

2016

 

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May 2016

Platelet-mediated modulation of adaptive immunity.

Iannacone M

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January 2016

IFNa gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment.

Catarinella M, Monestiroli A, Escobar G, Fiocchi A, Tran NL, Aiolfi R, Marra P, Esposito A, Cipriani F, Aldrighetti L, Iannacone M, Naldini L, Guidotti LG, Sitia G

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October 2016

Inflammatory monocytes hinder antiviral B cell responses.

Sammicheli S*, Kuka M*, Di Lucia P, Jimenez de Oya N, De Giovanni M, Fioravanti J, Cristofani C, Maganuco CG, Fallet B, Ganzer L, Sironi L, Mainetti M, Ostuni R, Larimore K, Greenberg PD, De La Torre JC, Guidotti LG, Iannacone M

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January 2016

Spatiotemporal dynamics of effector CD8+ T cell responses within the liver.

Inverso D, Iannacone M

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September 2016

Protective and pathogenic T cell responses to virus infections.

Iannacone M, Chisari FV, Guidotti LG

 

2015

 

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April 2015

Immunosurveillance of the liver by intravascular effector CD8+ T cells.

Guidotti LG*, Inverso D*, Sironi L, Di Lucia P, Fioravanti J, Fiocchi A, Vacca M, Aiolfi R, Sammicheli S, Mainetti M, Ganzer L, Cataudella T, Raimondi A, Gonzalez- Aseguinolaza G, Protzer U, Ruggeri ZM, Chisari FV, Isogawa M, Sitia G, Iannacone M

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January 2015

A luminescent poly(amidoamine)-iridium complex as a new singlet-oxygen sensitizer for photodynamic therapy.

Maggioni D, Galli M, D'Alfonso L, Inverso D, Dozzi MV, Iannacone M, Collini M, Ferruti P, Ranucci E, D'Alfonso G

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November 2015

Mouse models of HBV pathogenesis.

Iannacone M, Guidotti LG

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May 2015

Hepatic effector CD8+ T cell dynamics.

Iannacone M

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November 2015

Viral pathogenesis.

Iannacone M, Guidotti LG

 

2014

 

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April 2014

PTPN22 controls virally-induced autoimmune diabetes by modulating cytotoxic T lymphocyte responses in an epitope-specific manner.

Fousteri G, Jofra T, Di Fonte R, Kuka M, Iannacone M, Battaglia M

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June 2014

The role of lymph node sinus macrophages in host defense.

Kuka M, Iannacone M

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December 2014

In vivo flow mapping in complex vessel networks by single image correlation

Sironi L, Bouzin M, Inverso D, D'Alfonso L, Pozzi P, Cotelli F, Guidotti LG, Iannacone M, Collini M, Chirico G

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May 2014

Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release.

Ilyinskii PO, Roy CJ, O'Neil CP, Browning EA, Pittet LA, Altreuter DH, Alexis F, Tonti E, Shi J, Basto PA, Iannacone M, Radovic-Moreno AF, Langer RS, Farokhzad OC, von Andrian UH, Jhonston LP, Kishimoto TK

 
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October 2013

Biophosphonates target B cells to enhance humoral immune responses.

Tonti E, Jimenez de Oya N, Galliverti G, Moseman EA, Di Lucia P, Amabile A, Sammicheli S, De Giovanni M, Sironi L, Chevrier N, Sitia G, Gennari L, Guidotti LG, von Andrian UH, Iannacone M

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August 2013

Effector CD8 T cell trafficking within the liver

Guidotti LG, Iannacone M

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September 2013

Antigen availability determines CD8+ T cell-dendritic cell interaction kinetics and effector/memory fate decisions.

Henrickson SE, Perro M, Loughhead SM, Senman B, Stutte S, Quigley M, Alexe G, Iannacone M, Flynn MP, Omid S, Jesneck JL, Imam S, Mempel TR, Mazo IB, Haining WN, Von Andrian UH

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November 2013

Antiplatelet therapy in the prevention of hepatitis B virus-associated hepatocellular carcinoma.

Sitia G, Iannacone M, Guidotti LG

2013

 

 

2012

 

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September 2012

Chemokine guidance of central memory T cells is critical for anti-viral recall responses in lymph nodes.

Sung JH, Zhang H, Moseman EA, Alvarez D, Iannacone M, Henrickson SE, de la Torre JC, Luster AD, Von Andrian UH

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April 2012

Follicular helper NKT cells provide CD1d-restricted help to B cells eliciting specific antibody responses in the absence of CD4+T cells.

Tonti E, Fedeli M, Napolitano A, Iannacone M, von Andrian UH, Guidotti LG, Abrignani S, Casorati G, 

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August 2012

Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B.

Sitia G, Aiolfi R, Di Lucia P, Mainetti M, Fiocchi A, Mingozzi F, Esposito A, Ruggeri ZM, Chisari FV, Iannacone M, Guidotti LG

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March 2012

B cell maintenance of subcapsular sinus macrophages protects against a fatal viral infection independent of adaptive immunity.

Moseman EA, Iannacone M, Bosurgi L, Tonti E, Chevrier N, Tumanov A, Fu Y-X, Hacohen N, von Andrian UH