My laboratory’s work centers on understanding how immune responses are orchestrated within local tissue niches. Recent breakthroughs in intravital imaging and spatially resolved omics have enabled us to visualize and quantify interactions at cellular resolution in living organisms, revealing unprecedented details about how immune cells — and even non-immune cells — behave and communicate.

In our lab, we combine these powerful tools — high-resolution imaging, single-cell sequencing, and advanced computational analyses — to dissect how local processes converge to influence immune outcomes. By focusing on phenomena such as how T cells exert their immune surveillance and examining immunological crosstalk across different tissues, we aim to bridge the gap between discrete molecular events and broader physiological consequences. This holistic perspective is particularly relevant in complex conditions like infectious diseases and cancer, where local cell-to-cell interactions can be a pivotal driver of disease progression. Ultimately, our goal is to uncover novel principles of tissue immunity and leverage them for more precise immunotherapeutic strategies.